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Narrowing of the carotid artery is generally caused by atherosclerosis – hardening of the arteries with plaque buildup. The affected area is usually the location in the neck where the artery splits into two branches. Your doctor will evaluate the benefits of repair by considering the risk factors involved. A "significant" narrowing of the artery is considered to be 50%, though surgery is generally not performed until the narrowing is greater than 60% or 70%. Your doctor will usually check for narrowing with a Duplex Ultrasound test; an MRI(A) or angiogram may also be useful in the diagnosis. Options for repair include surgery (endarterectomy) or angioplasty/ stenting.

The stroke risk associated with surgery is 1-3%. Stenting is believed to have a similar stroke risk to surgery at this time. These procedures are not performed to improve any current symptoms, but rather to prevent any new or recurrent events. Whether or not symptoms are present, carotid disease is associated with increased risk of stroke, though that risk is increased when symptoms are present. Symptomatic patients may face a 25% risk of stroke in 1.5 years, while the risk for asymptomatic patients may be only 2-3% per year. Options for repair include surgery (endarterectomy) orangioplasty/stenting. The stroke risk associated with surgery is 1-3%.

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