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Alameda Hospital began as Alameda Sanatorium, which was founded in 1894 by registered nurse Kate Creedon. Creedon converted a small house into a six-bed facility with a desperately needed operating room. Before its founding, there was no medical facility of any kind in Alameda. Horse drawn carriages and bicycles brought doctors to patients’ homes and patients to doctors’ offices. Surgeries were often performed on the kitchen table using chloroform as the most common anesthetic.

By 1901 the hospital had expanded to a three-story building and established a nursing school.
In 1925 a new building was built on its present site. As progressive then as it is now, this 110-room facility was the first hospital in the West to be completely wired for electricity.

Numerous expansions over the years have resulted in today's comprehensive, state-of-the-art, 135-bed facility.